Articles

The following articles are hyperlinked to the original journal article or an abstract of the article:

 

Bioanalysis Articles

Absorption, PK and Excretion Articles

PK/PD Articles

Distribution Articles

Metabolism Articles

Structural Elucidation Articles

Biomarker Articles

Biochemistry Articles

Cell Biology Articles

Immunology Articles

Molecular Biology Articles

Pharmacology Articles

 

Bioanalysis Articles

 

Detection of Tetrahydrobiopterin by LC–MS/MS in Plasma from Multiple Species

Yuwen Zhao, Jerry Cao, Yuan-Shek Chen, Colin Patrick, Benjamin Chien, Alphonsus Cheng, and Erik D. Foehr

BIOANALYSIS, 1, 5, 895–903 (2009)

 

Pharmacokinetics of Sapropterin in Patients with Phenylketonuria

(QPS was acknowledged for supporting the bioanalysis of Tetrahydrobiopetin plasma samples)

Franςois Feillet, Lorne Clarke, Concetta Meli, Mark Lipson, Andrew A. Morris, Paul Harmatz, Diane R. Mould, Bruce Green, Alex Dorenbaum, Marcello Giovannini, and Erik Foehr

CLINICAL PHARMACOKINETIC, 47, 12, 817–825 (2008)

 

Urinary TIINE Concentrations in a Randomized Controlled Trial of Doxycycline in Knee Osteoarthritis –Implications of the Lack of Association Between TIINE Levels and Joint Space Narrowing

(QPS was acknowledged for supporting the bioanalysis of TIINE urinary samples)

Ivan G. Otterness, Kenneth D. Brandt, Marie-Pierre Hellio Le Graverand, and Steven A. Mazzuca

ARTHRITIS & RHEUMATISM, 56, 11, 3644–3649 (2007)

 

Clusters of biochemical markers are associated with radiographic subtypes of osteoarthritis (OA) in subject with familial OA at multiple sites. The GARP study

(QPS was acknowledged for supporting the bioanalysis of TIINE urinary samples)

I. Meulenbelt, M. Kloppenburg, H.M. Kroon, J.J. Houwing-Duistermaat, P. Garnero, M.-P. Hellio- Le Graverand, J. DeGroot, and P.E. Slagboom

OSTEOARTHRITIS AND CARTILAGE, 15, 4, 379–385 (2007)



Determination of Rifalazil, a Potent Antibacterial Agent, in Human Plasma by Liquid-Liquid Extraction and LC-MS/MS

Marita Larsson, Arthur F. Michaelis, Yongdong Zhu, and Kumar Ramu

JOURNAL OF CHROMATOGRAPHY B, 859, 1, 103–110 (2007)

 

Association between concentrations of urinary type II collagen neoepitope (uTIINE) and joint space narrowing in patients with knee osteoarthritis

(QPS was acknowledged for supporting the bioanalysis of TIINE urinary samples)

M.-P. Hellio Le Graverand, K.D. Brandt, S.A. Mazzuca, B.P. Katz, R. Buck, K.A. Lane, E. Pickering, O.V. Nemirovskiy, T. Sunyer, and D.J. Welsch

OSTEOARTHRITIS AND CARTILAGE, 14, 11, 1189–1195 (2006)


A High-Performance Liquid Chromatography–Tandem Mass Spectrometry Assay of the Androgenic Neurosteroid 3α-Androstanediol (5α-Androstane-3α,17β-diol) in Plasma

Doodipala S. Reddy, Lata Venkatarangan, Benjamin Chien, and Kumar Ramu

STEROIDS, 70, 13, 1, 879–885 (2005)

 

A High-Performance Liquid Chromatography–Tandem Mass Spectrometry Method for the Determination of Pharmacokinetics of Ganaxolone in Rat, Monkey, Dog and Human Plasma

Kumar Ramu, Gilbert N. Lam, and Ben Chien

JOURNAL OF CHROMATOGRAPHY B, 751, 1, 49–59 (2001)

 

Development of a High-Performance Liquid Chromatographic-Tandem Mass Spectrometric Method for the Determination of Pharmacokinetics of Co 102862 in Mouse, Rat, Monkey and Dog Plasma

Kumar Ramu, Gilbert N. Lam, and Benjamin Chien

JOURNAL OF CHROMATOGRAPHY B, 749, 1, 1–15 (2000)

 

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Absorption, PK and Excretion Articles

 

Criteria for selecting pharmacokinetic repeat study samples

S. Peter King, Bruce J. Aungst, and Huey-Shin L. Shen

BIOANALYSIS 1, 8, 1415–1418 (2009)

 

Role of Intestinal P-Glycoprotein in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents

C. Edwin Garner, Eric G. Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen, and Frank W. Lee

DRUG METABOLISM AND DISPOSITION, 36, 1102–1110 (2008)

 

N-in-1 Dosing Pharmacokinetics in Drug Discovery: Experience, Theoretical and Practical Considerations

Kan He, Mingxin Qian, Harvey Wong, Stephen A. Bai, Bing He, Bernice Brogdon, James E. Grace, Baomin Xin, Jingtao Wu, Shelly X. Ren, Hang Zeng, Yuzhong Deng, Danielle M. Graden, Timothy V. Olah, Steve E. Unger, Joseph M. Luettgen, Robert M. Knabb, Donald J. Pinto, Patrick Y.S. Lam, James Duan, Ruth R. Wexler, Carl P. Decicco, David D. Christ, and Scott J. Grossman

JOURNAL OF PHARMACEUTICAL SCIENCES, 97, 7, 2568–2580 (2008)

 

Evaluating Barriers to Bioavailability In Vivo: Validation of a Technique for Separately Assessing Gastrointestinal Absorption and Hepatic Extraction

Laura Letendre, Mark Scott, Glenn Dobson, Ismael Hidalgo, and Bruce Aungst

PHARMACEUTICAL RESEARCH, 21, 8, 1457–1462 (2004)

 

β-Cyclodextrin as a Suitable Solubilizing Agent for In Situ Absorption Study of Poorly Water-Soluble Drugs

Masako Oda, Hiroshi Saitoh, Michiya Kobayashi, and Bruce J. Aungst

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 280, 1, 95–102 (2004)

 

Development and In Vivo Evaluation of Buccal Tablets Prepared Using Danazol Sulfobutylether 7 β Cyclodextrin (SBE 7) Complexes

Ashwinkumar C. Jain, Bruce J. Aungst, and Moji Christianah Adeyeye

JOURNAL OF PHARMACEUTICAL SCIENCES, 91, 7, 1659–1668 (2002)

 

Formulation and Food Effects in the Oral Absorption of a Poorly Water Soluble, Highly Permeable Antiretroviral Agent

Bruce J. Aungst, Nhung H. Nguyen, Nancy J. Taylor, and Dilbir S. Bindra

JOURNAL OF PHARMACEUTICAL SCIENCES, 91, 6, 1390–1395 (2002)

 

In Vitro Permeation of β Lactam Antibiotics across Rat Jejunum and its Correlation with Oral Bioavailability in Humans

Hiroshi Saitoh, Bruce J. Aungst, Masashi Tohyama, Yuko Hatakeyama, Keiko Ohwada, Michiya Kobayashi, Hiroko Fujisaki, and Katsumi Miyazaki

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 54, 4, 445–488 (2002)

 

Organ Perfusion and Mass Spectrometry: A Timely Merger for Drug Development

C. Gerald Curtis, Ben Chien, David Bar-Or, and Kumar Ramu

CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2, 1, 77–86 (2002)

 

The Influence of Fatty Acids and Fatty Alcohols on Skin Permeability

Bruce J. Aungst

DRY SKIN AND MOISTURIZERS, CHEMISTRY AND FUNCTION, (M. LODEN, ED.), CRC PRESS (2000)

 

Intestinal Permeation Enhancers

Bruce J. Aungst

JOURNAL OF PHARMACEUTICAL SCIENCES, 89, 4, 429–442 (2000)

 

Caco 2 Permeability and Secretory Transport of HIV Protease Inhibitors and other Lipophilic Compounds, and the Influences of Donor and Reservoir Additives

Bruce J. Aungst, Nhung H. Nguyen, James P. Bulgarelli, and Kristi Oates-Lenz

PHARMACEUTICAL RESEARCH, 17, 10, 1175–1180 (2000)

 

Region-Dependent Disappearance of Vinblastine in Rat Small Intestine and Characterization of P Glycoprotein-mediated Efflux System in the Jejunum

Akira Nakayama, Hiroshi Saitoh, Masako Oda, Masahiko Takada, and Bruce J. Aungst

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 11, 4, 317–324 (2000)

 

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PK/PD Articles

 

CNTO 530: Molecular Pharmacology in Human UT-7EPO Cells and Pharmacokinetics and Pharmacodynamics in Mice

P.J. Bugelski, R.J. Capocasale, D. Makropoulos, D. Marshall, P.W. Fisher, J. Lu, R. Achuthanandam, T. Spinka-Doms, D. Kwok, D. Graden, A. Volk, T. Nesspor, I.E. James, and C. Huang

JOURNAL OF BIOTECHNOLOGY, 134, 1-2,171–180 (2008)

 

Pharmacodynamics of Recombinant Human Erythropoietin in Murine Bone Marrow

Peter J. Bugelski, Thomas Nesspor, Amy Volk, Joanne O’Brien, Dorie Makropoulos, Kim Shamberger, Paul W. Fisher, Ian James, Danielle Graden, and Renold J. Capocasale

PHARMACEUTICAL RESEARCH, 25, 2, 369–378 (2007)

 

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Distribution Articles

 

Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development
Eric G. Solon, Alain Schweitzer, Markus Stoeckli, and Brendan Prideaux

THE AAPS JOURNAL, ACCEPTED AND TO BE PUBLISHED 2010

 

Autoradiography: High-Resolution Molecular Imaging in Pharmaceutical Discovery and Development

Eric G. Solon

EXPERT OPINION DRUG DISCOVERY, 2, 4, 503–514 (2007)

 

Distribution of Radioactivity in Bone and Related Structures following Administration of [14C]Dalbavancin to New Zealand White Rabbits

Eric G. Solon, James A. Dowell, Jonghui Lee, S. Peter King, and Bharat D. Damle

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 51, 8, 3008–3010 (2007)

 

Ghrelin and Cholecystokinin in Term and Preterm Human Breast Milk

Jennifer A. Kierson, Darlise M. DiMatteo, Robert G. Locke, Amy B. Mackley, and Michael L. Spear

ACTA PARDIATRICA, 95, 8, 991–995 (2006)

 

Radiation Dose to Abdominal Organs of the Mouse due to 90Y in the Urinary Bladder

Joel Lazewatsky, Yihong Ding, David Onthank, Paula Silva, Eric Solon, and Simon Robinson

CANCER BIOTHERAPY & RADIOPHARMACEUTICALS, 18, 3, 413–419 (2003)

 

Whole-Body Autoradiography In Drug Discovery

(This paper is the cover of the December 2002 issue of CURRENT DRUG METABOLISM)

Eric G. Solon, Suresh K. Balani, and Frank W. Lee

CURRENT DRUG METABOLISM, 3, 5, 451–462 (2002)

 

Methods Determining Phosphor Imaging Limits of Quantitation in Whole Body Autoradiography Rodent Tissue Distribution Studies Affect Predictions of 14C Human Dosimetry

Eric G. Solon and Frank Lee

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGY METHODS, 46, 2, 83–91 (2002)

 

Quantitative Whole Body Autoradiography in the Pharmaceutical Industry. Survey Results on Study Design, Methods, and Regulatory Compliance

Eric G. Solon and Lori Kraus

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGY METHODS, 46, 2, 73–81 (2002)

 

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Metabolism Articles

 

Prodrugs to Reduce Presystemic Metabolism

Bruce J. Aungst and Nicole Matz

PRODRUGS: CHALLENGES AND REWARDS, (V. STELLA, ED.), AAPS PRESS (2007)

 

Effect of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide], a Human Tumor Necrosis Factor α-Converting Enzyme Inhibitor, on the Disposition of Methotrexate: A transporter-Based Drug-Drug Interaction Case Study

Gang Luo, C. Edwin Garner, Hao Xiong, Hanbo Hu, Lauren E. Richards, Kim L. R. Brouwer, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Helen Shen, Frank W. Lee, and Liang-Shang Gan

DRUG METABOLISM AND DISPOSITION, 35, 835–840 (2007)

 

Limited Interaction between Tacrolimus and P-Glycoprotein in the Rat Small Intestine

Hiroshi Saitoh, Yuko Saikachi, Mikako Kobayashi, Michiko Yamaguchi, Masako Oda, Yoshimitsu Yuhki, Kazuhito Achiwa, Koji Tadano, Yasushi Takahashi, and Bruce J. Aungst

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 28, 1, 34–42 (2006)

 

Relationship Between Loperamide-Induced Sedative Effect and Digoxin Pharmacokinetics in Healthy Japanese Subjects

Michiya Kobayashi, Hiroshi Saitoh, Michiko Yamaguchi, Takeshi Saito, Hiroyoshi Fujita, Manabu Suno, Kazuo Matsubara, and Bruce J. Aungst

PHARMACEUTICAL RESEARCH, 22, 3, 413–418 (2005)

 

Increased Hepatobiliary Clearance of Unconjugated Thyroxine Determines DMP 904-Induced Alterations in Thyroid Hormone Homeostasis in Rats

Harvey Wong, Lois D. Lehman-McKeeman, Mary F. Grubb, Scott J. Grossman, Vasanthi M. Bhaskaran, Eric G. Solon, Helen S. L. Shen, Ronald J. Gerson, Bruce D. Car, Bitao Zhao, and Brian Gemzik

TOXICOLOGY SCIENCES, 84, 232–242 (2005)

 

Concurrent Induction and Mechanism-based Inactivation of CYP3A4 by an L Valinamide Derivative

Gang Luo, Jianrong Lin, William D. Fiske, Renke Dai, Tian J. Yang, Sean Kim, Michael Sinz, Edward Lecluyse, Eric G. Solon, James M. Brennan, Irma H. Benedek, Summer Jolley, Darryl Gilbert, Lifei Wang, Frank W. Lee, and Liang-Shang Gan

DRUG METABOLISM AND DISPOSITION, 31, 1170–1175 (2003)

 

Secretory Transport of Methylprednisolone Possibly Mediated by P-Glycoprotein in Caco 2 Cell

Ayako Oka, Masako Oda, Hiroshi Saitoh, Akira Nakayama, Masahiko Takada, and Bruce J. Aungst

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 25, 3, 393–396 (2002)

 

Interaction of Ritonavir on Tissue Distribution of a [14C]L-Valinamide, a Potent Human Immunodeficiency Virus-1 protease Inhibitor, in Rats using Quantitative Whole-body Autoradiography

(This paper is the cover of the November 2002 issue of DRUG METABOLISM AND DISPOSITION)

Eric G. Solon, Suresh K. Balani, Gang Luo, Tian J. Yang, Paula J. Haines, Lifei Wang, Tonya Demond, Sharon Diamond, David D. Christ, Liang-Shang Gan, and, Frank W. Lee

DRUG METABOLISM AND DISPOSITION, 30, 11, 1164–1169 (2002)

 

In Vivo Metabolism and Mass Balance of 4-[4-Fluorophenoxy]benzaldehyde Semicarbazone in Rats

Kumar Ramu, Gilbert N. Lam, and Helen Hughes

DRUG METABOLISM AND DISPOSITION, 28, 10, 1153–1161 (2000)

 

Metabolic Impairment Elicits Brain Cell-type Selective Changes in Oxidative Stress and Cell Death

Larry C. Park, Noel Y. Calingasan, Koji Uchida, Hui Zhang, and Gary E. Gibson

JOURNAL OF NEUROCHEMISTRY, 74, 1, 114–124 (2000)

 

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Structural Elucidation Articles

 

Translesion Synthesis Across 1,N2-Ethenoguanine by Human DNA Polymerases

Jeong-Yun Choi, Hong (Alex) Zang, Karen C. Angel, Ivan D. Kozekov, Angela K. Goodenough, Carmelo J. Rizzo, and F. Peter Guengerich

CHEMICAL RESEARCH IN TOXICOLOGY, 19, 6, 879–886 (2006)

 

Translesion Synthesis Across Polycyclic Aromatic Hydrocarbon Diol Epoxide Adducts of Deoxyadenosine by Sulfolobus solfataricus DNA Polymerase Dpo4

Hong (Alex) Zang, Adriana Irimia, Jeong-Yun Choi, Karen C. Angel, Lioudmila V. Loukachevitch, Martin Egli, and F. Peter Guengerich

CHEMICAL RESEARCH IN TOXICOLOGY, 19, 6, 859–867 (2006)

 

Translesion Synthesis Across O6-Alkylguanine DNA Adducts by Recombinant Human DNA Polymerases

Jeong-Yun Choi, Goutam Chowdhury, Hong (Alex) Zang, Karen C. Angel, Choua C. Vu, Lisa A. Peterson, and F. Peter Guengerich

JOURNAL OF BIOLOGICAL CHEMISTRY, 281, 50, 38244–38256 (2006)

 

Calcium is a Cofactor of Polymerization but Inhibits Pyrophosphorolysis by the Sulfolobus solfataricus DNA Polymerase Dpo4

Adriana Irimia, Hong (Alex) Zang, Lioudmila V. Loukachevitch, Robert L. Eoff, F. Peter Guengerich, and Martin Egli

BIOCHEMISTRY, 45, 19, 5949–5956 (2006)

 

Efficient and High Fidelity Incorporation of dCTP Opposite 7,8-Dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA Polymerase Dpo4

Hong (Alex) Zang, Adriana Irimia, Jeong-Yun Choi, Karen C. Angel, Lioudmila V. Loukachevitch, Martin Egli, and F. Peter Guengerich

JOURNAL OF BIOLOGICAL CHEMISTRY, 281, 4, 2358–2372 (2006)

 

Quantitation of Four Guanine Oxidation Products from Reaction of DNA with Varying Doses of Peroxynitrite

Hongbin Yu, Lata Venkatarangan, John S. Wishnok, and Steven R. Tannenbaum

CHEMICAL RESEARCH IN TOXICOLOGY, 18, 12, 1849–1857 (2005)

 

Kinetic Analysis of Steps in the Repair of Damaged DNA by Human O6-Alkylguanine DNA-Alkyltransferase

Hong (Alex) Zang, Qingming Fang, Anthony E. Pegg, and F. Peter Guengerich

JOURNAL OF BIOLOGICAL CHEMISTRY, 280, 35, 30873–30881 (2005)

 

DNA Adduct Bypass Polymerization by Sulfolobus solfataricus Dpo4. Analysis and Crystal Structures of Multiple Base-Pair Substitution and Frameshift Products with the Adduct 1,N2-Ethenoguanine

(This paper is the cover of the Aug. 19, 2005 issue of JOURNAL OF BIOLOGICAL CHEMISTRY)

Hong (Alex) Zang, Angela K. Goodenough, Jeong-Yun Choi, Adriana Irimia, Lioudmila V. Loukachevitch, Ivan D. Kozekov, Karen C. Angel, Carmelo J. Rizzo, Martin Egli, and F. Peter Guengerich

JOURNAL OF BIOLOGICAL CHEMISTRY, 280, 33, 29750–29764 (2005)

 

Kinetics of Nucleotide Incorporation Opposite DNA Bulky Guanine-N2 Adducts by Processive Bacteriophage T7 Polymerase (Exonuclease-) and HIV-1 Reverse Transcriptase

Hong (Alex) Zang, Thomas M. Harris, and F. Peter Guengerich

JOURNAL OF BIOLOGICAL CHEMISTRY, 280, 2, 1165–1178 (2005)

 

Kinetics of Nucleotide Incorporation Opposite Polycyclic Aromatic Hydrocarbon-DNA Adducts by Processive Bacteriophage T7 Polymerase

Hong (Alex) Zang, Thomas M. Harris, and F. Peter Guengerich

CHEMICAL RESEARCH IN TOXICOLOGY, 18, 2, 389–400 (2005)

 

Synthesis and Noncovalent DNA-Binding Properties of Thiazole Derivatives Related to Leinamycin

Leonid Breydo, Hong (Alex) Zang, and Kent S. Gates

TETRAHEDRON LETTERS, 45, 29, 5711–5716 (2004)

 

Sequence Specificity of DNA Alkylation by the Antitumor Natural Product Leinamycin

Hong (Alex) Zang and Kent S. Gates

CHEMICAL RESEARCH IN TOXICOLOGY, 16, 12, 1539–1546 (2003)

 

Characterization of Eptifibatide during Drug Formulation Stability Assays

Ronghua Wang, Debby Feder, and Frank Hsieh

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 33, 5, 1181–1187 (2003)

 

DNA Alkylation by Leinamycin Can Be Triggered by Cyanide and Phosphines

Hong Zang, Leonid Breydo, Kaushik Mitra, Jeffrey Dannaldson, and Kent S. Gates

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 11, 12, 1511–1515 (2001)

 

Thiol-Independent DNA Alkylation by Leinamycin

(Abstracted in Chemical and Engineering News 2001, Mar. 5, p. 35)

Leonid Breydo, Hong Zang, Kaushik Mitra, and Kent S. Gates

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 123, 9, 2060–2061 (2001)

 

Site-Specifically Located 8-Amino-2’-deoxyguanosine: Thermodynamic Stability and Mutagenic Properties in Escherichia coli

Lata Venkatarangan, A. Sivaprasad, Francis Johnson, and Ashis K. Basu

NUCLEIC ACIDS RESEARCH, 29, 7, 1458–1463 (2001)

 

DNA Binding and Alkylation by the "Left Half" of Azinomycin B

Hong (Alex) Zang and Kent S. Gates

BIOCHEMISTRY, 39, 48, 14968–14975 (2000)

 

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Biomarkers

 

HIP/RPL29 Antagonizes VEGF and FGF2 Stimulated Angiogenesis by Interfering with HS-Dependent Responses

Sonia D'Souza, Weidong Yang, Dario Marchetti, Caroline Muir (Becker), Mary C. Farach-Carson, and Daniel D. Carson

JOURNAL OF CELL BIOCHEMISTRY,105, 5,1183–1193 (2008)

 

Upregulation of Macrophage Endothelial Lipase by Toll-Like Receptors 4 and 3 Modulates Macrophage IL-10 and IL-12 Production

Xun Wang, Weijun Jin, and Daniel J. Rader

CIRCULATION RESEARCH, 100, 1008–1015 (2007)

 

Hypoxia Increases VEGF-A Production by Prostate Cancer and Bone Marrow Stromal Cells and Initiates Paracrine Activation of Bone Marrow Endothelial Cells

Caroline Muir (Becker), Leland W. K. Chung, Daniel D. Carson, and Mary C. Farach-Carson

CLINICAL & EXPERIMENTAL METASTASIS, 23, 1, 75–86 (2006)

 

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Biochemistry

 

Hepatic Proprotein Convertases Modulate HDL Metabolism

Weijun Jin, Xun Wang, John S. Millar, Thomas Quertermous, George H. Rothblat, Jane M. Glick, and Daniel J. Rader

CELL METABOLISM, 6, 129–136 (2007)

 

Determinants of Specificity of MDM2 for the Activation Domains of p53 and p65: Proline27 Disrupts the MDM2-Binding Motif of p53

Susan Carr Zondlo, Aaron E. Lee, and Neal J. Zondlo

BIOCHEMISTRY, 45, 39, 11945–11957 (2006)

 

Production of Recombinant Bartonella henselae 17 kDa Protein for Development of Antibody-Capture Enzyme-Linked Immunosorbent Assay

Chien Chang Loa, Eli Mordechai, Richard C. Tilton, and Martin E Adelson

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 55, 1, 1–7 (2006)

 

Serological Diagnosis of Human Babesiosis by IgG Enzyme-Linked Immunosorbent Assay

Chien Chang Loa, Martin E. Adelson, Eli Mordechai, I. Ralphaelli, and Richard C. Tilton

CURRENT MICROBIOLOGY, 49, 385–389 (2004)

 

Expression and Purification of Turkey Coronavirus Nucleocapsid Protein in Escherichia coli

Chien Chang Loa, Tsang L. Lin, Ching C. Wu, Thomas A. Bryan, Tom Hooper, and Donna Schrader

JOURNAL OF VIROLOGICAL METHODS, 116, 161–167 (2004)

 

Comparison of Western Immunoblots and the C6 Lyme Antibody Test for the Laboratory Detection of Lyme Disease

Elena Mogilyansky, Chien Chang Loa, Martin E. Adelson, Eli Mordechai, and Richard C. Tilton

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 11, 5, 924–929 (2004)

 

Expression and Functional Characterization of Recombinant Turkey IFN-r

Chien Chang Loa, Ming K. Hsieh, Tsang L. Lin, and Ching C. Wu.

JOURNAL OF ANIMAL AND VETERINARY ADVANCES, 2, 12, 648–653 (2003)

 

Inhibition of the α-Ketoglutarate Dehydrogenase Complex Alters Mitochondrial Function and Cellular Calcium Regulation

Hsueh-Meei Huang, Hui Zhang, Hui Xu, and Gary E. Gibson

BIOCHIMICA ET BIOPHYSICA ACTA, 1637, 1, 119–126 (2003)

 

Specific Mucosal IgA Immunity in Turkey Poults Infected with Turkey Coronavirus

Chien Chang Loa, Tsang L. Lin, Ching C. Wu, Thomas A. Bryan, Tom Hooper, and Donna Schrader

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 88, 57–64 (2002)

 

Purification of Turkey Coronavirus by Sephacryl Size-Exclusion Chromatography

Chien Chang Loa, Tsang L. Lin, Ching C. Wu, Thomas A. Bryan, Leon H. Thacker, Tom Hooper, and Donna Schrader

JOURNAL OF VIROLOGICAL METHODS, 104, 187–194 (2002)

 

The SANT Domain of Ada2 is Required for Normal Acetylation of Histones by the Yeast SAGA Complex

David E. Sterner, Xun Wang, Melissa H. Bloom, and Shelley L. Berger

JOURNAL OF BIOLOGICAL CHEMISTRY, 277, 8178–8186 (2002)

 

Antigenic Relationship of Turkey Coronavirus Isolates from Different Geographic Locations in the United States

Tsang L. Lin, Chien Chang Loa, Ching C. Wu, Thomas A. Bryan, Tom Hooper, and Donna Schrader

AVIAN DISEASES, 46, 2, 466–472 (2002)

 

Oxidative Stress Increases Internal Calcium Stores and Reduces a Key Mitochondrial Enzyme

Gary E. Gibson, Hui Zhang, Hui Xu, Larry C. H. Park, and Thomas M. Jeitner

BIOCHIMICA ET BIOPHYSICA ACTA, 1586, 2, 177–189 (2002)

 

Assessment of Membrane Potentials of Mitochondrial Populations In Living Cells

Hui Zhang, Hsueh-Meei Huang, R. C. Carson, J. Mahmood, H. M. Thomas, and Gary E. Gibson

ANALYTICAL BIOCHEMISTRY, 298, 2, 170–180 (2001)

 

Differential Alterations in Antioxidant Capacity in Cells from Alzheimer Patients

Gary E. Gibson, Hui Zhang, K. F. R. Sheu, and Larry C. Park

BIOCHIMICA ET BIOPHYSICA ACTA, 1502, 319–329 (2000)

 

Detection of Antibody to Turkey Coronavirus by Antibody-Capture Enzyme-Linked Immunosorbent Assay Utilizing Infectious Bronchitis Virus Antigen

Chien Chang Loa, Tsang L. Lin, Ching C. Wu, Thomas A. Bryan, Leon H. Thacker, Tom Hooper, and Donna Schrader

AVIAN DISEASES, 44, 498-506 (2000)

 

Phospholipid Composition and Levels are not Altered in Fibroblasts bearing Presenilin-1 Mutations

E. J. Murphy, Hui Zhang, S. Sorbi, S. I. Rapoport, and Gary E. Gibson

BRAIN RESEARCH BULLETIN, 52, 3, 207–212 (2000)

 

Mitochondrial Damage in Alzheimer's Disease Varies with Apolipoprotein E Genotype

Gary E. Gibson, V. Haroutunian, Hui Zhang, Larry C. Park, Q. Shi, M. Lesser, R.C. Mohs, R. K. Sheu, and J. P. Blass

ANNAL OF NEUROLOGY, 48, 3, 297–303 (2000)

 

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Cell Biology

 

Roles for the Drs2p-Cdc50p Complex in Protein Transport and Phosphatidylserine Asymmetry of the Yeast Plasma Membrane

Sophie Chen*, Jiyi Wang*, Baby-Periyanayaki Muthusamy, Ke Liu, Sara Zare, Raymond J Andersen, and Todd R. Graham

*These authors contributed equally to this work

TRAFFIC, 7, 11, 1503–1517 (2006)

 

Increased Susceptibility of Spinal Muscular Atrophy Fibroblasts to Camptothecin-induced Cell Death

Wenlan Wang, Darlise DiMatteo, Vicky L. Funanage, and Mena Scavina

MOLECULAR GENETIC AND METABOLISM, 85, 1, 38–45 (2005)

 

Mitochondrial Function in Fibroblasts with Aging in Culture and/or Alzheimer's disease

Hsueh-Meei Huang, Corinne Fowler, Hui Xu, Hui Zhang, and Gary E. Gibson

NEUROBIOLOGY OF AGING, 26, 6, 839–848 (2005)

 

Perlecan Knockdown in Metastatic Prostate Cancer Cells Reduces Heparin-Binding Growth Factor Responses In Vitro and Tumor Growth In Vivo

Cristiana Savorè, Chu Zhang, Caroline Muir (Becker), Riting Liu, Jeffrey Wyrwa, Jun Shu, Haiyen E. Zhau, Leland W. K. Chung, Daniel D. Carson, and Mary C. Farach-Carson

CLINICAL & EXPERIMENTAL METASTASIS, 22, 5, 377–390 (2005)

 

Mitochondrial Heterogeneity Within and Between Different Cell Types

Hsueh-Meei Huang, Corinne Fowler, Hui Zhang, and Gary E. Gibson

NEUROCHEMICAL RESEARCH, 29, 3, 651–658 (2004)

 

Drs2p-Coupled Aminophospholipid Translocase Activity in Yeast Golgi Membranes and Relationship to In Vivo Function

Paramasivam Natarajan, Jiyi Wang, Zhaolin Hua, and Todd R. Graham.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES U. S. A., 101, 29, 10614–10619 (2004)

 

Co-culture with Astrocytes or Microglia Protects Metabolically Impaired Neurons

Larry C. Park, Hui Zhang, and Gary E. Gibson

MECHANISM OF AGING AND DEVELOPMENT, 123, 1, 21–27 (2001)

 

CD47, a Ligand for the Macrophage Fusion Receptor, Participates in Macrophage Multinucleation

Xin Han, Hyacinth Sterling, Yongmei Chen, Charles Saginario, Eric J. Brown, William A. Frazier, Frederik P. Lindberg, and Agnès Vignery

JOURNAL OF BIOLOGICAL CHEMISTRY, 275, 48, 37984–37992 (2000)

 

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Immunology

 

Immune Distribution and Localization of Phosphoantigen-Specific Vγ2Vδ2 T cells in Lymphoid and Nonlymphoid Tissues in Mycobacterium Tuberculosis Infection

Dan Huang, Yun Shen, Liyou Qiu, Crystal Y. Chen, Ling Shen, Jim Estep, Robert Hunt, Daphne Vasconcelos, George Du, Pyone Aye, Andrew A. Lackner, Michelle H. Larsen, William R. Jacobs, Jr., Barton F. Haynes, Norman L. Letvin, and Zheng W. Chen

INFECTION AND IMMUNITY, 76, 1, 426–36 (2008)

 

Lyme Disease Associated with Alzheimer’s Disease

Laurence Meer-Scherrer, Chien Chang Loa, Martin E. Adelson, Eli Mordechai, and Richard C. Tilton

CURRENT MICROBIOLOGY, 52, 330–332 (2006)

 

Clinical Latency and Reaction of AIDS-Related Mycobacterial Infections

Yun Shen, Ling Shen, Prabhat Sehgal, Dan Huang, Liyou Qiu, George Du, Norman L. Letvin, and Zheng W. Chen

JOURNAL OF VIROLOGY, 78, 24, 14023–32 (2004)

 

Development of Vγ2Vδ2+ T Cell Responses during Active Mycobaterial Coinfection of Simian Immunodeficiency Virus-Infected Macaques Requires Control of Viral Infection and Immune Competence of CD4+ T Cells

Ling Shen, Yun Shen, Dan Huang, Liyou Qiu, Prabhat Sehgal, George Z Du, Michael D Miller, Norman L Letvin, and Zheng W Chen

JOURNAL OF INFECTIOUS DISEASES, 190, 8 1438–47 (2004)

 

Immune Biology of Macaque Lymphocyte Populations during Mycobacterial Infection

X. Lai, Y. Shen, D. Zhou, P. Sehgal, L. Shen, M. Simon, L. Qiu, N. L. Letvin, and Z. W. Chen

CLINICAL & EXPERIMENTAL IMMUNOLOGY, 133, 182–192 (2003)

 

Inhibition of Adaptive Vγ2Vδ2+ T-Cell Responses during Active Mycobacterial Coinfection of Simian Immunodeficiency Virus SIVmac-Infected Monkeys

Dejiang Zhou, Xiaomin Lai, Yun Shen, Prabhat Sehgal,Ling Shen, Meredith Simon, Liyou Qiu, Dan Huang, George Z. Du, Qifan Wang, Norman L. Letvin, and Zheng W. Chen

JOURNAL OF VIROLOGY, 77, 5, 2998–3006 (2003)

 

Adaptive Immune Response of Vγ2Vδ2+ T Cells During Mycobacterial Infections

Yun Shen, Dejiang Zhou, Liyou Qiu, Xioamin Lai, Meredith Simon, Ling Shen, Zhongchen Kou, Qifan Wang, Liming Jiang, Jim Estep, Robert Hunt, Michelle Clagett, Prabhat K. Sehgal, Yunyaun Li, Xuejun Zeng, Craig T. Morita, Michael B. Brenner, Norman L. Letvin, Zheng W. Chen

SCIENCE, 295, 2255–2258 (2002)

 

Induction of an AIDS Virus-Related Tuberculosis-Like Disease in Macaques: a Model of Simian Immunodeficiency Virus-Mycobacterium

Yun Shen, Dejiang Zhou, Laura Chalifoux, Ling Shen, Meredith Simon, Xuejun Zeng, Xioamin Lai, Yunyuan Li, Prabhat Sehgal, Norman L. Letvin, and Zheng W. Chen

INFECTION AND IMMUNITY, 70, 2, 869–77 (2002)

 

The effect of Immunosuppression on Protective Immunity of Turkey Poults Against Infection with Turkey Coronavirus

Chien Chang Loa, Tsang L. Lin, and Ching C. Wu.

COMPARATIVE IMMUNOLOGY, MICROBIOLOGY, AND INFECTIOUS DISEASES, 25, 2, 127–138 (2002)

 

In Vivo T-Lymphocyte Activation and Transient Reduction Viral Replication in Macaques Infected with Simian Immunodeficiency Virus

Zheng W. Chen, Yun Shen, Dejiang Zhou, Meredith Simon, ZhongChen Kou, David Lee-Parritz, Ling Shen, Prabhat Sehgal, and Norman L. Letvin

JOURNAL OF VIROLOGY, 75, 10, 4713–4720 (2001)

 

Factors Affecting Mitogenic Response of Turkey Lymphocytes

Chien Chang Loa, Tsang L. Lin, and Ching C. Wu

ACTA VETERINARIA BRNO, 70, 433–442 (2001)

 

Humoral and Cellular Immune Responses in Turkey Poults Infected with Turkey Coronavirus

Chien Chang Loa, Tsang L. Lin, Ching C. Wu, Thomas A. Bryan, Leon H. Thacker, Tom Hooper, and Donna Schrader

POULTRY SCIENCE, 80, 1416–1424 (2001)

 

Down-regulation of Macaque γδ+ T cells in Lymphoid Compartments after Rectal Infection with SIVsmmPBj14

Zheng W. Chen, Yun Shen, Ian C. Davis , Ling Shen , Norman L. Letvin, and Patricia N. Fultz

JOURNAL OF MEDICAL PRIMATOLOGY, 29, 3–4, 143–7 (2000)

 

Prolonged Dominance of Clonally Restricted CD4+ T Cells in Macaques Infected with Simian Immunodeficiency Viruses

Zheng W. Chen, Yun Shen, Zhongchen Kou, Chris Ibegbu, Dejiang Zhou, Ling Shen, Paul Morrison, Christine Bogle, Harold M. McClure, Andre J. Nahmias, Prahbat K. Sehgal, and Norman L. Letvin

JOURNAL OF VIROLOGY, 74, 6, 7442–7450 (2000)

 

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Molecular Biology Articles

 

Molecular Regulation of Macrophage Reverse Cholesterol Transport

Xun Wang and Daniel J. Rader

CURRENT OPINION IN CARDIOLOGY, 22, 4, 368–372 (2007)

 

Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast

Ainslie B. Parsons, Andres Lopez, Inmar E. Givoni, David E. Williams, Christopher Gray, Justin Porter, Gordon Chua, Richelle Sopko, Renee L. Brost, Cheuk-Hei Ho, Jiyi Wang, Troy Ketela, Charles Brenner, Julie A. Brill, G. Esteban Fernandez , Todd C. Lorenz , Gregory S. Payne, Satoru Ishihara, Yoshikazu Ohya, Brenda Andrews, Timothy R. Hughes, Brendan J. Frey, Todd R. Graham, Raymond J. Andersen, and Charles Boone.

CELL, 126, 3, 611–625 (2006)

 

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Mutation Analysis

 

Genetic Correction of Splice Site Mutation in Purified and Enriched Myoblasts Isolated from mdx5cv Mice

Katie Maguire, Takayuki Suzuki, Darlise DiMatteo, Hetal Parekh-Olmedo, and Eric Kmiec

BMC MOLECULAR BIOLOGY, 10, 10–15 (2009)

 

Genetic Conversion of an SMN2 Gene to SMN1: a Novel Approach to the Treatment of Spinal Muscular Atrophy

Darlise DiMatteo, Stephanie Callahan, and Eric B. Kmiec

EXPERIMENTAL CELL RESEARCH, 314, 4, 878–86 (2008)

 

Analysis of the Ser786Pro Interleukin-4 Receptor α Allelic Variant in Allergic and Non-Allergic Asthma and Its Functional Consequences

Ryan P. Andrews, Lesley Burrell, Lillian Rosa-Rosa, Christie M. Cunningham, Jennifer L. Brzezinski, Jonathan A. Bernstein, and Gurjit K. Khurana Hershey

CLINICAL IMMUNOLOGY, 100, 3, 298–304 (2001)

 

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Expression Analysis

 

Gene Expression in Mouse Brain following Chronic Hypoxia: Role of Sarcospan in Glial Cell Death

Dan Zhou*, Jiyi Wang*, Matthew A. Zapala, Jin Xue, Nicholas J. Schork, and Gabriel G. Haddad

*These authors contributed equally to this work

PHYSIOLOGICAL GENOMICS, 32, 370–379 (2007)

 

Novel Genes Identified by Manual Annotation and Microarray Expression Analysis in the Pancreas

Joan M. Mazzarelli, Peter White, Regina Gorski, John Brestelli, Deborah F. Pinney, Athanasios Arsenlis, Alexey Katokhin, Olga Belova, Vera Bogdanova, Eugenij Elisafenko, Marina Gubina, Lilia Nizolenko, Polina Perelman, Mikhail Puzakov, Alexandre Shilov, Vladimir Trifonoff, Nadezhda Vorobjeva, Nikolay Kolchanov, Klaus H. Kaestner and Christian J. Stoeckert Jr.

GENOMICS, 88, 752–761 (2006)

 

Maturation Stage-Specific Regulation of Megakaryopoiesis by Pointed-Domain Ets Proteins

Liyan Pang, Hai-Hui Xue, Gabor Szalai, Xun Wang, Yuhuan Wang, Dennis K. Watson, Warren J. Leonard, Gerd A. Blobel, and Mortimer Poncz

BLOOD, 108, 7, 2198-2206 (2006)

 

Orthogonal Analysis of C/EBPβ Targets in vivo During Liver Proliferation

Joshua R. Friedman, Brian Larris, Phillip P. Le, T. Harshani Peiris, Athanasios Arsenlis, Jonathan Schug, John W. Tobias, Klaus H. Kaestner, and Linda E. Greenbaum

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES U. S. A., 101, 35, 12986–12991 (2004)

 

Transcriptional Program of the Endocrine Pancreas in Mice and Humans

Klaus H. Kaestner, Catherine S. Lee, L. Marie Scearce, John E. Brestelli, Athanasios Arsenlis, Phillip Phuc Le, Kristen A. Lantz, Jonathan Crabtree, Angel Pizarro, Joan Mazzarelli, Deborah Pinney, Steve Fischer, Elisabetta Manduchi, Christian J. Stoeckert, Jr., Gerard Gradwohl, Sandra W. Clifton, Juliana R. Brown, Hiroshi Inoue, Corentin Cras-Me´neur, and M. Alan Permutt

DIABETES, 52, 7, 1604–10 (2003)

 

Control of Megakaryocyte-Specific Gene Expression by GATA-1 and FOG-1: Role of Ets Transcription Factor

Xun Wang, John D. Crispino, Danielle L. Letting, Minako Nakazawa, Mortimer Poncz, and Gerd A. Blobel

EMBO JOURNAL, 21, 19, 1–10 (2002)

 

Reconstitution of a Functional Human Type II IL-4/IL-13 Receptor in Mouse B Cells: Demonstration of Species Specificity

Ryan P. Andrews, Lillian Rosa Rosa, Michael O. Daines and Gurjit K. Khurana Hershey

JOURNAL OF IMMUNOLOGY, 166, 1716–1722 (2001)

 

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Gene Sequence Analysis

 

Comparison of 3’ End Encoding Regions of Turkey Coronavirus Isolates from Indiana, North Carolina, and Minnesota

Chien Chang Loa, Tsang L. Lin, and Ching C. Wu

INTERVIROLOGY, 49, 230–238 (2006)

 

Differential Detection of Turkey Coronavirus, Infectious Bronchitis Virus, and Bovine Coronavirus by a Multiplex Polymerase Chain Reaction

Chien Chang Loa, Tsang L. Lin, and Ching C. Wu

JOURNAL OF VIROLOGICAL METHODS, 131, 86–91 (2006)

 

Reciprocal DNA Topoisomerase II Cleavage Events at 5’-TATTA-3’ Sequence in MLL and AF-9 Create Homologous Single-stranded Overhangs that Anneal to Form der(11) and der(9) Genomic Breakpoint Junctions in Treatment-related AML without Further Processing

Ryan J. Whitmarsh*, Charles Saginario*, Ya Zhuo, Eva Hilgenfeld, Eric F. Rappaport, Maureen D. Megonigal, Martin Carroll, Mingli Liu, Neil Osheroff, Nai-Kong V. Cheung, Diana J. Slater, Thomas Ried, Turid Knutsen, Ian A. Blair, and Carolyn A. Felix

*These authors contributed equally to this work

ONCOGENE, 22, 8448–8459 (2003)

 

Existence of Gene 5 Indicates Close Genomic Relationship of Turkey Coronavirus to Avian Infectious Bronchitis Virus but not to Bovine Coronavirus

Tsang L. Lin, Chien Chang Loa, and Ching C. Wu

ACTA VIROLOGICA, 46, 2, 107–116 (2002)

 

Characterization of Turkey Coronavirus from Turkey Poults with Acute Enteritis

Chien Chang Loa, Tsang L. Lin, Ching C. Wu, Thomas A. Bryan, Tom Hooper, and Donna Schrader

VETERINARY MICROBIOLOGY, 84, 1-2, 179–186 (2002)

 

Molecular Identification and Characterization of Turkey IFN-γ Gene

Chien Chang Loa, Ming K. Hsieh, Tsang L. Lin, and Ching C. Wu

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, 130B, 579–584 (2001)

 

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Cloning

 

Complete Sequences of 3’ End Encoding Regions for Structural Protein Genes of Turkey Coronavirus

Tsang L. Lin, Chien Chang Loa, and Ching C. Wu

VIRUS RESEARCH, 106, 1, 61–70 (2004)

 

Expression Cloning of the STRL33/BONZO/TYMSTR Ligand Reveals Elements of CC, CXC, and CX3C Chemokines

Alyson Wilbanks, Susan Carr Zondlo, Kristine Murphy, Simona Mak, Dulce Soler, Patricia Langdon, David P. Andrew, Lijun Wu, and Michael Briskin

JOURNAL OF IMMUNOLOGY, 166, 5145–5154 (2001)

 

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Pharmacology

 

Macrophage ABCA1 and ABCG1, but not SR-BI, Promote Macrophage Reverse Cholesterol Transport In Vivo

Xun Wang, Heidi L. Collins, Mollie Ranalletta, Ilia V. Fuki, Jeffrey T. Billheimer, George H. Rothblat, Alan R. Tall, and Daniel J. Rader

JOURNAL OF CLINICAL. INVESTIGATION, 117, 8 2216–2224 (2007)

 

Selective Inhibition of Eosinophil Influx into the Lung by Small Molecule CC Chemokine Receptor 3 Antagonists in Mouse Models of Allergic Inflammation

Anuk M. Das, Krishna G. Vaddi, Kimberly A. Solomon, Candice Krauthauser, Xiaosui Jiang, Kim W. McIntyre, Xiao Xia Yang, Eric Wadman, Patricia Welch, Maryanne Covington, Danielle Graden, Krishnaswamy Yeleswaram, James M. Trzaskos, Robert C. Newton, Sandhya Mandlekar, Soo S. Ko, Percy H. Carter, and Paul Davies

JOURNAL OF PHARMACOLOGY EXPERIMENTAL THERAPEUTICS, 318:411–417 (2006)

 

Leptin Enhances Lung Maturity in the Fetal Rat

Susan M. Kirwin, Vineet Bhandari, Darlise Dimatteo, Carol Barone, Linda Johnson, Saptarashi Paul, Alan R. Spitzer Avinash Chander, Sandra G. Hassink, and Vicky L. Funanage

PEDIATRIC RESEARCH, 60, 2, 200–2004 (2006)

 

Mechanism of Protective Action of Bicyclol Against CCl-Induced Liver Injury in Mice

Geng Tao Liu, Yan Li, Huai Ling Wei, Hui Zhang, Ji Yan Xu, and Ling Hong Yu

LIVER INTERNATIONAL, 25, 4, 872–879 (2005)

 

Toxicity of Novel Anti-Hepatitis Drug Bicyclol: a Preclinical Study

Geng-Tao Liu, Yan Li, Huai-Ling Wei, Hong Lu, Hui Zhang, Yu-Gui Gao, and Ling-Zhi Wang

WORLD JOURNAL OF GASTROENTEROLOGY, 7, 11, 5, 665–71 (2005)

 

Raising HDL Cholesterol without Inducing Hepatic Steatosis and Hypertriglyceridemia by a Selective LXR Modulator

Bowman Miao, Susan Zondlo, Sandy Gibbs, Debra Cromley, Vinayak P. Hosagrahara, Todd G. Kirchgessner, Jeffrey Billheimer, and Ranjan Mukherjee

JOURNAL OF LIPID RESEARCH, 45, 8, 1410–1417 (2004)

 

Differential Effect of the GPIIb/IIIa Antagonist Orbofiban on Human Platelet Aggregate Formation in vitro

Adrienne L. Racanelli, Sandra K. Gibbs, Susan Carr Zondlo, Dietmar A. Seiffert, Steven M. Friedman, and Giora Z. Feuerstein

THROMOBOSIS RESEARCH, 110, 2, 99–105 (2003)

 

Effects of Orally Active Glycoprotein IIb/IIIa Antagonists on Platelet CD40 Ligand (CD154) Expression and Platelet-Heteroaggregate Formation

Susan Carr Zondlo, Xinkang Wang, and Giora Z. Feuerstein

THROMOBOSIS RESEARCH, 106, 1, 35–40 (2002)

 

Leptin and Estradiol as Related to Change in Pubertal Status and Body Weight

Kimberly A. Larmore, Darlise O'Connor, Tami I. Sherman, Vicky L. Funanage, Sandra G. Hassink, and Karen Oerter Klein

MEDICAL SCIENCES MONITOR, 8, 3, CR206–10 (2002)

 

Leptin: a New Growth Factor for the Small Intestine

Karim Alavi, Marshall Z. Schwartz Rajeev Prasad, Darlise O'connor, and Vicky L. Funanage

JOURNAL OF PEDIATRIC SURGERY, 37, 3, 327–30 (2002)

 

Immaturity or Starvation? Longitudinal Study of Leptin Levels in Premature Infants

Michael L. Spear, Sandra G. Hassink, Kathleen Leef, Darlise M. O'Connor, Susan M. Kirwin, Robert Locke, Robert Gorman, Vicky L. Funanage

BIOLOGY OF THE NEONATE, 80, 1, 35–40 (2001)

 

Abnormalities in Oxidative Processes in Non-neuronal Tissues from Patients with Alzheimer's Disease

Gary E. Gibson and Hui Zhang

JOURNAL ALZHEIMER'S DISEASE, 3, 3, 329–338 (2001)

 

Novel Effect of Leptin on Small Intestine Adaptation

Philip Y. Pearson, Darlise M. O'Connor, Marshall Z. Schwartz

JOURNAL OF SURGICAL RESEARCH, 97, 2, 192–195 (2001)

 

Antiretroviral Agents Restore Mycobacterium-Specific T-cell Immune Responses and Facilitate Controlling a Fatal Tuberculosis-Like Disease in Macaques Coinfected with Simian Immunodeficiency Virus and Mycobacterium bovis BCG

Shen Y, Shen L, Sehgal PK, Zhou D, Simon M, Miller M, Enimi EA, Henckler B, Chalifoux L, Sehgal N, Gastron M, Letvin NL and Chen ZW

JOURNAL OF VIROLOGY, 75, 18, 8690–8696 (2001)

 

Dopaminergic Cell Death Induced by MPP+, Oxidant and Specific Neurotoxicants Shares the Common Molecular Mechanism

Hong S. Chun, Gary E. Gibson, Lorraine A. DeGiorgio, Hui Zhang, Vincent J. Kidd, and Jin H. Son

JOURNAL OF NEUROCHEMISTRY, 76, 4, 1010–1021 (2001)

 

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